Community Health Workers (CHWs) have played a key role in the response to the COVID-19 pandemic. However, it is essential that health center administrators, managers, and care teams understand how to effectively leverage the skills and experience of CHWs and adequately support and prepare them for this work. This resource, prepared for the Association of Clinicians for the Underserved’s STAR² Center by the National Association of Community Health Workers, contains guidance and action items to help health center teams effectively incorporate these essential workers as part of vaccine rollout efforts.