One of the most crucial roles health center leadership plays is taking care of the wellbeing and mental health of all staff, including their own. While mental health challenges among the healthcare workforce is not a new phenomenon, the COVID-19 pandemic and other societal and traumatic events only served to further exacerbate the problem. This factsheet provides health center leadership with a better understanding of the different mental health struggles their workforce may face and identifies strategies, related to compensation equity and inclusive benefits, to address these ongoing workplace challenges.